AccuFill® BSM is an engineered calcium phosphate mineral compound.1 It flows readily to fill subchondral defects, crystallizes and hardens quickly in an endothermic reaction at 37° C to form a nanocrystalline, macroporous scaffold in the bone. Over time, through cell-mediated remodeling, AccuFill® BSM is resorbed and replaced with new bone.
Important Information: The use of AccuFill® BSM is not intended to be intrinsic to the stability of the bony structure. Radiographic studies should be used to confirm that the adjacent cortical bone is intact.
AccuFill® BSM Performance
|Formulation||Proprietary next generation apatite.
Mimics chemical structure of human bone.
|Facilitates cell-mediated remodeling.|
Flowable inside cancellous bone.
15 minutes of working time.
|No need to remove subchondral bone.
No phase separation from injection pressure.
Interdigitates easily for complete defect fill.
Long window for implantation; intraoperative flexibility.
|Setting||Endothermically sets in 10 minutes at 37°C.||Sets hard after closure, no thermal necrosis.|
65% total porosity; 1-300 μm pore size.
10 MPa compressive strength.
|Nanocrystalline structure and high surface area facilitate remodeling and bony ingrowth.
Physical properties comparable to cancellous bone.
Remodeled vs. dissolved.
|Remodels with new bone growth.|
AccuFill® BSM = Ca10-x(M)x(PO4)6-x(HPO4,CO3)x(OH)2-x = Bone*1
AccuFill® BSM is manufactured by Etex, a subsidiary of Zimmer Biomet and leader in bioresorbable bone substitute materials. The company is headquartered in MIT´s University Park in Cambridge, Massachusetts, a world renowned center for biotech research and innovation.
- 1 Tofighi, et al. New Generation of Synthetic, Bioresorbable and Injectable Calcium Phosphate Bone Substitute Materials: Alpha-bsm, Beta-bsm and Gamma- bsm; JBBTE. 2009; 2:39.
- * M = metal ions
Learn more about the Zimmer Biomet Etex platform of orthobiologic augmentation materials.