Bone Marrow Lesions (BML) are MRI-visible defects in the subchondral bone. BML can only be seen on fat-suppressed MRI sequences (T2FS, PDFS, etc.) where they appear as a hazy white area against the background of darker bone. Pathologists have shown that BML represent a healing response to trauma such as micro trabecular fractures of the subchondral bone.1

Coronal Bone Marrow Lesion
Sagittal Bone Marrow Lesion

MRI of chronic Bone Marrow Lesions

In these patients, current treatment guidelines recommend an initial course of conservative care which may heal the defect. If the defect remains, The Subchondroplasty® (SCP®) Procedure may be an option.

During The SCP® Procedure, AccuFill® BSM, an injectable, flowable, engineered calcium phosphate bone substitute is used to fill a subchondral bone defect. AccuFill® BSM crystallizes and hardens in an endothermic reaction at 37° C to form a nanocrystalline, macroporous scaffold in the bone. Over time, through cell-mediated remodeling, AccuFill® BSM is resorbed and replaced with new bone.

To learn more about The SCP® Procedure, visit the Zimmer Biomet Institute Calendar of Courses for a listing of Seminars and Hands-on Bioskills Workshops.


  • 1 Eriksen EF, Ringe JD. Bone marrow lesions: a universal bone response to injury? Rheumatol Int. 2012;32(3):575–584.